Regenerative & Repair

TB-500

Thymosin Beta-4 Fragment - Thymosin β-4 fragment studied for actin regulation and tissue repair.

TB-500 is a synthetic version of the naturally occurring peptide Thymosin β-4. Research interest centres on its regulation of actin, cell migration and its reported role in tissue-repair and flexibility models.

As a synthetic form of the naturally occurring Thymosin β-4, TB-500 is studied less for a single receptor and more for its upstream effect on the actin cytoskeleton, which touches migration, angiogenesis and flexibility endpoints. It is a common comparator and combination partner in tissue-repair protocols alongside BPC-157.

TB-500 specifications

Sequence
Synthetic fragment of Thymosin β-4
Presentation
Lyophilised powder
Documented purity
99.62% by HPLC
Available sizes
10mg ($85)
Archived COA lots
4
Intended use
Laboratory research use only. Not for human or veterinary use.

Studied pathways

  • Actin regulation - Binds and sequesters G-actin, a mechanism linked to cell migration and repair in study models.
  • Cell migration - Studied for its role in directing reparative cells toward sites of tissue stress.

Reported mechanisms in the literature

  • Actin regulation - As a synthetic form of Thymosin β-4, it is studied for binding and sequestering G-actin - a mechanism linked to cell migration and tissue remodelling in repair research. (Goldstein et al.)
  • Reparative cell recruitment - Investigated for directing reparative and endothelial cells toward sites of tissue stress, and for its reported role in flexibility and recovery models. (Sosne et al.)

TB-500 frequently asked questions

Is TB-500 the same as Thymosin β-4?

TB-500 is a synthetic version of the naturally occurring peptide Thymosin β-4. Some suppliers instead sell a shorter active fragment; ours is documented on the lot COA. It is a research material only.

Is TB-500 approved for human use?

No. It has no regulatory approval for human use and is not a medicine or supplement. All available data is preclinical. It is supplied for in-vitro laboratory research only.

What is TB-500 studied for?

Chiefly actin regulation, cell migration and tissue-repair signalling in animal and cell models. Findings are preclinical and do not describe effects in humans.

Documented to 99.62% purity by HPLC · third-party COA every lot · from $85 · For laboratory research use only.

Related Regenerative & Repair compounds

  • BPC-157 - Synthetic pentadecapeptide studied for VEGF and growth-factor receptor signalling.
  • BPC-157 / TB-500 - Co-formulated repair-research blend in a single vial.
  • GHK-Cu - Copper tripeptide studied in skin-remodelling research.
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