Regenerative & Repair

GHK-Cu

Copper-Peptide Complex - Copper tripeptide studied in skin-remodelling research.

GHK-Cu is a naturally occurring copper tripeptide complex studied extensively for its role in extracellular-matrix remodelling, collagen synthesis and antioxidant signalling in dermatological research.

GHK-Cu sits at the intersection of peptide and trace-metal biology, and much of its research interest follows from the copper it carries into the cell as much as the tripeptide itself. Gene-expression studies have made it one of the more mechanistically characterised compounds in skin and matrix research.

GHK-Cu specifications

Sequence
Glycyl-L-histidyl-L-lysine · Cu²⁺
Presentation
Lyophilised powder
Documented purity
99.90% by HPLC
Available sizes
50mg ($40), 100mg ($55)
Archived COA lots
6
Intended use
Laboratory research use only. Not for human or veterinary use.

Studied pathways

  • Matrix remodelling - Studied for modulation of collagen and glycosaminoglycan synthesis in fibroblast models.
  • Copper transport - Acts as a copper-delivery complex, a mechanism linked to numerous downstream enzymatic pathways.

Reported mechanisms in the literature

  • Collagen & ECM - Studied for modulation of collagen and glycosaminoglycan synthesis and for gene-expression shifts associated with skin remodelling in fibroblast models. (Pickart et al.)
  • Cu²⁺ delivery - Acts as a copper-delivery complex - a mechanism linked to numerous downstream antioxidant and enzymatic pathways studied in dermatological research. (Pickart & Margolina)

GHK-Cu frequently asked questions

What is GHK-Cu?

GHK-Cu is a naturally occurring copper-tripeptide complex (glycyl-L-histidyl-L-lysine bound to copper). It is one of the most-studied peptides in skin and matrix-remodelling research.

Is GHK-Cu approved as a drug?

No. It appears in cosmetic formulations but is not an approved drug for any human therapeutic use. Here it is supplied strictly for laboratory research.

What is GHK-Cu researched for?

Extracellular-matrix remodelling, collagen synthesis, antioxidant signalling and tissue repair - primarily in cell and animal models.

Documented to 99.90% purity by HPLC · third-party COA every lot · from $40 · For laboratory research use only.

Related Regenerative & Repair compounds

  • BPC-157 - Synthetic pentadecapeptide studied for VEGF and growth-factor receptor signalling.
  • TB-500 - Thymosin β-4 fragment studied for actin regulation and tissue repair.
  • BPC-157 / TB-500 - Co-formulated repair-research blend in a single vial.
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