Metabolic

MOTS-c

Mitochondrial-Derived Peptide - Mitochondrial-derived peptide studied for metabolic regulation.

MOTS-c is a mitochondrial-derived peptide studied for its role as a regulator of metabolic homeostasis and insulin sensitivity in cellular research.

MOTS-c is one of a small class of mitochondrial-derived peptides - encoded by mitochondrial rather than nuclear DNA - which is itself the reason for much of the research attention it receives. Studies focus on its AMPK-linked role in metabolic stress and exercise physiology.

MOTS-c specifications

Sequence
16-amino-acid mitochondrial-derived peptide
Presentation
Lyophilised powder
Documented purity
99.66% by HPLC
Available sizes
10mg ($65)
Archived COA lots
3
Intended use
Laboratory research use only. Not for human or veterinary use.

Studied pathways

  • AMPK activation - Investigated for AMPK-pathway activation linked to cellular energy regulation.

Reported mechanisms in the literature

  • Metabolic regulation - A mitochondrial-derived peptide studied for AMPK-pathway activation linked to cellular-energy regulation and insulin sensitivity. (Lee et al.)

MOTS-c frequently asked questions

What is MOTS-c?

A mitochondrial-derived peptide - unusually, encoded by mitochondrial DNA - studied as a regulator of metabolic homeostasis and insulin sensitivity in cellular research.

Is MOTS-c approved for human use?

No. It is a research material only, with preclinical data only. It is not a medicine or supplement.

What is it studied for?

AMPK-pathway activation and its role in cellular energy metabolism, primarily in cell and animal models.

Documented to 99.66% purity by HPLC · third-party COA every lot · from $65 · For laboratory research use only.

Related Metabolic compounds

  • GLP-3 RT - Triple-receptor GLP research compound (GLP-1/GIP/glucagon class).
  • GLP-2 TZ - Dual GIP/GLP-1 receptor co-agonist studied in glucose-handling and energy-balance research.
  • 5-Amino-1MQ - Small-molecule NNMT inhibitor studied in metabolism research.
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