5-Amino-1MQ
NNMT Inhibitor (Small Molecule) - Small-molecule NNMT inhibitor studied in metabolism research.
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), a target studied in adipocyte-metabolism and cellular-energy research.
Unlike most of the catalogue, 5-Amino-1MQ is a small molecule rather than a peptide, and it acts by inhibiting an enzyme (NNMT) rather than engaging a receptor. That places it upstream of the NAD⁺ salvage pathway, which is why it is often studied alongside NAD⁺ itself in metabolism research.
5-Amino-1MQ specifications
- Sequence
- 5-amino-1-methylquinolinium (small molecule)
- Presentation
- Lyophilised powder
- Documented purity
- 99.94% by HPLC
- Available sizes
- 50mg ($85)
- Archived COA lots
- 4
- Intended use
- Laboratory research use only. Not for human or veterinary use.
Studied pathways
- NNMT inhibition - Studied for modulation of NAD⁺ salvage and adipocyte energy metabolism.
Reported mechanisms in the literature
- NNMT inhibition - A small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied for modulation of the NAD⁺ salvage pathway and adipocyte energy metabolism. (Kraus et al.)
5-Amino-1MQ frequently asked questions
What is 5-Amino-1MQ?
A small-molecule inhibitor of the enzyme NNMT, a target studied in adipocyte-metabolism and cellular-energy research. It is most commonly supplied as the iodide salt.
Is it approved for human use?
No. It is a research chemical only, with preclinical data only, supplied for in-vitro laboratory study.
What is it researched for?
NNMT inhibition and its downstream effects on NAD⁺ metabolism and adipocyte energy handling in cell and animal models.
Documented to 99.94% purity by HPLC · third-party COA every lot · from $85 · For laboratory research use only.