KPV
Alpha-MSH C-Terminal Fragment - α-MSH C-terminal fragment studied for inflammatory signalling.
KPV is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone, studied for its reported anti-inflammatory activity without the pigmentary effects of the parent peptide.
Because KPV retains the anti-inflammatory activity of α-MSH without the receptor engagement responsible for pigmentation, it is studied as a cleaner probe of that pathway. Research emphasis is on epithelial and mucosal-barrier models rather than systemic endpoints.
KPV specifications
- Sequence
- Lysine-Proline-Valine (tripeptide)
- Presentation
- Lyophilised powder
- Documented purity
- 99.48% by HPLC
- Available sizes
- 10mg ($60)
- Archived COA lots
- 2
- Intended use
- Laboratory research use only. Not for human or veterinary use.
Studied pathways
- Inflammatory modulation - Investigated for downregulation of pro-inflammatory signalling in cellular models.
Reported mechanisms in the literature
- Inflammatory modulation - As the C-terminal tripeptide of α-MSH, it is studied for downregulation of pro-inflammatory NF-κB signalling without the pigmentary activity of the parent hormone. (Luger & Brzoska)
KPV frequently asked questions
What is KPV?
KPV is the lysine-proline-valine tripeptide fragment at the C-terminus of alpha-melanocyte-stimulating hormone, studied for anti-inflammatory activity in cell and animal models.
Is KPV approved for human use?
No. It has no regulatory approval and is not a medicine or supplement. It is a research material only, with preclinical data only.
How is KPV handled?
Supplied as a lyophilised powder, reconstituted in the lab per the researcher's protocol. We provide the compound and its COA, not dosing guidance.
Documented to 99.48% purity by HPLC · third-party COA every lot · from $60 · For laboratory research use only.
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