Cognitive & Nootropic

Semax

ACTH-Derived Research Peptide - ACTH-derived peptide studied for neuroprotection and cognitive modulation.

Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone, studied for its reported neuroprotective and cognitive-modulating activity in Russian and preclinical research.

Semax is a mainstay of Russian neuropeptide research, where it is studied for neuroprotective and cognitive endpoints, and much of its primary literature is published in that context. Its short ACTH-derived sequence and reported BDNF effects make it a frequent subject in neural-plasticity models.

Semax specifications

Sequence
Pro-Gly-Pro heptapeptide (ACTH 4-10 analog)
Presentation
Lyophilised powder
Documented purity
99.72% by HPLC
Available sizes
10mg ($60)
Archived COA lots
3
Intended use
Laboratory research use only. Not for human or veterinary use.

Studied pathways

  • BDNF expression - Studied for upregulation of brain-derived neurotrophic factor in neural models.
  • Neuroprotection - Investigated for protective activity under ischaemic and oxidative stress conditions.

Reported mechanisms in the literature

  • BDNF expression - An ACTH(4-10) analog studied for upregulation of brain-derived neurotrophic factor and downstream neural-plasticity signalling. (Myasoedov et al.)
  • Neuroprotection - Investigated for protective activity under ischaemic and oxidative-stress conditions in Russian and preclinical neuro-research. (Ashmarin et al.)

Semax frequently asked questions

What is Semax?

A synthetic peptide derived from a fragment of adrenocorticotropic hormone, studied for neuroprotective and cognitive-modulating activity, largely in Russian and preclinical research.

Is Semax approved for human use?

It is registered for some uses in Russia but is not an FDA-approved drug in the US. It is supplied here for laboratory research only.

What is it researched for?

BDNF signalling, neuroprotection and cognition in cell and animal models.

Documented to 99.72% purity by HPLC · third-party COA every lot · from $60 · For laboratory research use only.

Related Cognitive & Nootropic compounds

  • Selank - Tuftsin analog studied for anxiolytic signalling.
  • DSIP - Delta sleep-inducing peptide studied for sleep architecture.
  • Pinealon - Short peptide bioregulator studied for neural protection.
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