Melanocortin & Tone

PT-141

MC4 Receptor Agonist - Bremelanotide - MC4 receptor agonist studied in melanocortin signalling.

PT-141 (Bremelanotide) is a melanocortin-receptor agonist and metabolite of Melanotan II, studied for its central role in melanocortin-receptor signalling research via the MC4 receptor.

PT-141 (Bremelanotide) is the more receptor-selective metabolite of Melanotan II, focusing on central MC4 signalling, and a bremelanotide product has reached regulatory approval for a specific indication. Research here centres on that central pathway rather than pigmentation.

PT-141 specifications

Sequence
Bremelanotide — cyclic heptapeptide
Presentation
Lyophilised powder
Documented purity
99.60% by HPLC
Available sizes
10mg ($45)
Archived COA lots
2
Intended use
Laboratory research use only. Not for human or veterinary use.

Studied pathways

  • MC4 receptor - Studied for central-nervous-system arousal signalling distinct from vascular pathways.

Reported mechanisms in the literature

  • Central arousal signalling - A melanocortin-receptor agonist and metabolite of Melanotan II, studied for central arousal signalling via the MC4 receptor, distinct from vascular pathways. (Molinoff et al.)

PT-141 frequently asked questions

What is PT-141?

PT-141 (Bremelanotide) is a melanocortin-receptor agonist and metabolite of Melanotan II, studied for central arousal signalling via the MC4 receptor.

Is PT-141 approved?

A bremelanotide product is approved for a specific indication under prescription, but this material is not sold as a medicine - it is supplied for laboratory research only.

What is it researched for?

MC4-receptor activation and central-nervous-system arousal signalling.

Documented to 99.60% purity by HPLC · third-party COA every lot · from $45 · For laboratory research use only.

Related Melanocortin & Tone compounds

  • Melanotan II - Melanocortin agonist studied for pigmentation research.
  • Kisspeptin - Upstream regulator of the reproductive hormone axis.
  • HCG - Gonadotropin studied in reproductive-endocrinology research.
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