PT-141
MC4 Receptor Agonist - Bremelanotide - MC4 receptor agonist studied in melanocortin signalling.
PT-141 (Bremelanotide) is a melanocortin-receptor agonist and metabolite of Melanotan II, studied for its central role in melanocortin-receptor signalling research via the MC4 receptor.
PT-141 (Bremelanotide) is the more receptor-selective metabolite of Melanotan II, focusing on central MC4 signalling, and a bremelanotide product has reached regulatory approval for a specific indication. Research here centres on that central pathway rather than pigmentation.
PT-141 specifications
- Sequence
- Bremelanotide — cyclic heptapeptide
- Presentation
- Lyophilised powder
- Documented purity
- 99.60% by HPLC
- Available sizes
- 10mg ($45)
- Archived COA lots
- 2
- Intended use
- Laboratory research use only. Not for human or veterinary use.
Studied pathways
- MC4 receptor - Studied for central-nervous-system arousal signalling distinct from vascular pathways.
Reported mechanisms in the literature
- Central arousal signalling - A melanocortin-receptor agonist and metabolite of Melanotan II, studied for central arousal signalling via the MC4 receptor, distinct from vascular pathways. (Molinoff et al.)
PT-141 frequently asked questions
What is PT-141?
PT-141 (Bremelanotide) is a melanocortin-receptor agonist and metabolite of Melanotan II, studied for central arousal signalling via the MC4 receptor.
Is PT-141 approved?
A bremelanotide product is approved for a specific indication under prescription, but this material is not sold as a medicine - it is supplied for laboratory research only.
What is it researched for?
MC4-receptor activation and central-nervous-system arousal signalling.
Documented to 99.60% purity by HPLC · third-party COA every lot · from $45 · For laboratory research use only.
Related Melanocortin & Tone compounds
- Melanotan II - Melanocortin agonist studied for pigmentation research.
- Kisspeptin - Upstream regulator of the reproductive hormone axis.
- HCG - Gonadotropin studied in reproductive-endocrinology research.